Lyle W. Hayes Ph.D., DABCC

EDUCATION AND CERTIFICATIONS

B.A.   Chemistry -Colorado College         

Ph.D.   Biochemistry/Biophysics -Oregon State University  

Clinical Resident, Clinical Chemistry and Toxicology -Oregon Health Sciences University

NYSDOH Laboratory Director Certificate of Qualification, Forensic Toxicology

Diplomat, American Board of Clinical Chemistry.

Full Member, Society of Forensic Toxicology

EXPERIENCE

Diredtor, Saratoga :Laboratories,  2008

Associate Director, Saratoga Laboratories. 2006-2007

Maintain laboratory certification and compliance with NYSHOH inspection and proficiency program for urine and hair drugs of abuse testing. Certify all results and maintain quality assurance and control. Supervise laboratory personnel and operations. Develop, validate, and implement analytic methods on GC/MS, GC/MS/MS and LC/MS/MS instrumentation.

Laboratory Director, Northeastern Toxicology Laboratory:  Forensic Toxicologist.   1996-2006

Established and maintained laboratory certification and compliance with NYSHOH inspection and proficiency program. Developed, validated, and implemented urine drugs of abuse EMIT screening and confirmation methodology with GC/MS.  Developed, validated and implemented Hair testing for Amphetamines, Opiates, Cocaine metabolites, Phencyclidine, and THCA and a highly-sensitive Ethylglucuronide method.

Chemistry Supervisor, Leonard Hospital and Seaton Health System, Troy, NY.  1993-1996.

Supervised chemistry and toxicology section of laboratory, including quality control and quality assurance and NYSDOH proficiency compliance.

Clinical Chemist, Dept. Clinical Pathology and Laboratory Medicine, Albany Medical Center, Albany, NY.            1991-1993

Responsible for supervision of stat lab, blood gas section, satellite and decentralized testing,

Clinical Chemistry Fellow, Dept. Clinical Pathology and Laboratory Medicine, Albany Medical Center, Albany, NY 1990‑1991

Assistant Professor, Clinical Chemistry, Department of Health Sciences, University of Wisconsin‑Milwaukee, 1985‑1989.

Taught clinical chemistry and toxicology for medical technology students.  Supervised Graduate Program.

Clinical Chemistry Resident, Clinical Pathology and Toxicology, School of Medicine, Oregon Health Sciences University.

REFERENCES

Upon Request

PUBLICATIONS

Hayes, L, Leque, J., Lin, J. and Rosano, T.  Ethyl Glucuronide endogenous levels and ethanol metabolism after low level exposure to ethanol. In preparation.

Hayes L, Krasseldt W, Bray, U. Correlation of morphine and blood alcohol levels in heroin overdose fatalities. In preparation.

Rosano T, Swift T and Hayes L.  Advances in catecholamine and metabolite measurement for the diagnosis of pheochromocytoma, a review.  Clinical Chemistry, 37:1854-67, 1991

Rosano T, Hayes L, Dybas M, Nazeer T, Ross J.  Evaluation of an immunoradiometric assay for cathepsin D concentration in breast and endometrial tumors. (Abstract) Clinical Chemistry, 37:1055, 1991

Otvos J, Hayes L, Jeyarajah E, Freedman D, Janjan N.  Relationship between the proton nuclear magnetic resonance properties of plasma lipoproteins and cancer. Clinical Chemistry, 37: 369-376, 1991.

Hayes L, Krasseldt W, Mueggler P, Concentrations of codeine and morphine in serum and urine after ingestion of poppy seeds. Clinical Chemistry, 33:806, 1987.

Hayes L, Swanson JR, Elevated ammonia results due to bacterial contamination of aca tubing.  Clinical Chemistry, 30:1882, 1984.

Hayes L, Rapid partial purification of angiotensin‑converting enzyme from human plasma‑ preliminary report. Clinical Chemistry, 30:1061, 1984.

Ching SF, Hayes L, Slakey LL, Angiotensin‑converting enzyme in cultured endothelial cells.  Synthesis, degradation and transfer to culture medium.  Atherosclerosis 3:581‑588, 1983.

Ching SF, Hayes L, Slakey LL, Angiotensin converting enzyme in cultured endothelial cells and growth medium.  Biochem Biophys Acta 657:222‑231, 1981.

Hayes L, Dickinson ES, Stevens AL, Slakey LL, A comparison of enzyme activities in cultured endothelial and smooth muscle cells from swine aorta.  Proc Natl Acad Sci 76:2532‑2535, 1979.

Hayes L, Goguen CA, Slakey LL, Angiotensin converting enzyme activity accumulation in medium from cultured endothelial cells.  Biochem Biophys Res Comm 82:1147‑1153, 1978.

Jungalwala FB, Hayes L, McCluer RH,  Determination of less than a nanomol of cerebrosides by high performance liquid chromatography with gradient elution analysis.  J Lipid Res 18:282‑292, 1977.

Hayes L, Jungalwala FB, Synthesis and turnover of cerebrosides and phos­phatidyl serine of myelin and microsomes in adult and developing rat brain.  Biochem J 160:195‑204, 1976.

Hayes L, Larrabee R, Relative turnover rates of proteins and peptides of rat liver fatty acid synthetase.  Biochem Biophys Res Comm 45:955‑963, 1971.

Hayes L, Tinsley IJ, Lowry RR, Utilization of fatty acid by developing steelhead sac fry Salmo gairdneri.  Comp Biochem Physiol 458:695‑707.

Hayes L, Lowry RR, Tinsley IJ,  Cholesterol interference in analysis of fatty acid methyl esters.  Lipids 6:65‑66, 1971.